Terada Y, Saito T, Fukuda Y, Suma H, Wanibuchi Y, Iwahashi T
Department of Cardiovascular Surgery, Mitsui Memorial Hospital, Tokyo, Japan.
Kyobu Geka. 1993 Jul;46(7):557-60.
Hemodynamic situation immediately after cardiopulmonary bypass was studied in cases of CABG using bilateral ITAs and right GEA. Though cardiac output was kept greater than 4.0 l/min, the blood pressure soon after weaning from cardiopulmonary bypass was low in patients who necessitated further circulatory assist, intraaortic balloon pumping (IABP) and/or additional surgical bypass procedure. In cases of CABG using arterial grafts and no vein graft, the perfusion pressure is most important to stabilize the hemodynamic status because low pressure may provoke peripheral vasoconstriction resulting in spastic reaction of the ITA and GEA. These arterial grafts seemed to keep the characteristics as the peripheral artery. Some papers pointed out less flow capacity of arterial grafts compared with that of saphenous vein graft, but CABG with arterial grafts alone was safe clinically if care is taken for keeping the perfusion pressure as high as preoperatively.
对采用双侧胸廓内动脉(ITA)和右侧胃网膜动脉(GEA)进行冠状动脉旁路移植术(CABG)的患者,研究了体外循环后即刻的血流动力学情况。尽管心输出量保持大于4.0升/分钟,但在需要进一步循环辅助、主动脉内球囊反搏(IABP)和/或额外手术旁路程序的患者中,体外循环撤离后不久血压较低。在使用动脉移植物而非静脉移植物进行CABG的情况下,灌注压力对于稳定血流动力学状态最为重要,因为低压可能引发外周血管收缩,导致ITA和GEA的痉挛反应。这些动脉移植物似乎保持着外周动脉的特性。一些文献指出,与大隐静脉移植物相比,动脉移植物的流量能力较小,但如果注意保持灌注压力与术前一样高,单纯使用动脉移植物进行CABG在临床上是安全的。