Sweis I E, McHenry C R, Jordan R B
Department of General Surgery, Case Western Reserve University School of Medicine, Cleveland, Ohio.
Plast Reconstr Surg. 1993 Aug;92(2):335-9. doi: 10.1097/00006534-199308000-00022.
The treatment of extraabdominal desmoid tumors remains controversial. Although a radical resection is associated with lower recurrence rates, the treatment of extensive, limb-threatening, or multifocal desmoids may require a more conservative excision with postoperative radiation and selective hormonal therapy. This approach would minimize functional deficits and improve cosmesis. If conservative resection with adjuvant radiotherapy and endocrine manipulation has failed and the tumor is compromising vital functions, then more radical resections may be justified.
腹外硬纤维瘤的治疗仍存在争议。尽管根治性切除与较低的复发率相关,但对于广泛的、威胁肢体的或多灶性硬纤维瘤,治疗可能需要更保守的切除,并辅以术后放疗和选择性激素治疗。这种方法将使功能缺陷最小化并改善美观。如果采用辅助放疗和内分泌调控的保守切除失败且肿瘤危及重要功能,那么更激进的切除可能是合理的。