Gasbarre L C, Nansen P, Monrad J, Gronveld J, Steffan P, Henriksen S A
Livestock and Poultry Sciences Institute, USDA, Beltsville, Maryland.
Res Vet Sci. 1993 May;54(3):340-4. doi: 10.1016/0034-5288(93)90132-y.
Serum anti-Ostertagia ostertagi and anti-Cooperia oncophora antibody responses were assessed in first season and second season calves grazing permanent paddocks. Calves without previous exposure to trichostrongyles were found to mount significant parasite-specific IgG1 antibody responses within two months of introduction to the pastures. A significant serum IgA response to O ostertagi and IgG2 responses to both O ostertagi and C oncophora antigens were also observed, but these responses were weaker. No consistent serum anti-trichostrongyle IgM responses were discernible in either age group. Second season grazing calves had significantly elevated IgG1, IgG2 and IgA antibody levels at turnout when compared to first season calves, but only IgA antibody levels against O ostertagi increased during the second grazing season. Comparison of serum antibody levels in first and second season calves grazed separately or together suggests that mixed grazing had no discernible effect on antigen priming.
在第一季和第二季于永久性牧场放牧的犊牛中评估了血清抗奥斯特他吉奥斯特他吉线虫和抗库珀线虫抗体反应。发现未曾接触过毛圆线虫的犊牛在引入牧场后的两个月内产生了显著的寄生虫特异性IgG1抗体反应。还观察到对奥斯特他吉奥斯特他吉线虫的显著血清IgA反应以及对奥斯特他吉奥斯特他吉线虫和库珀线虫抗原的IgG2反应，但这些反应较弱。在两个年龄组中均未观察到一致的血清抗毛圆线虫IgM反应。与第一季犊牛相比，第二季放牧的犊牛在放牧开始时IgG1、IgG2和IgA抗体水平显著升高，但在第二个放牧季节中仅针对奥斯特他吉奥斯特他吉线虫的IgA抗体水平有所增加。对分别或一起放牧的第一季和第二季犊牛血清抗体水平的比较表明，混合放牧对抗原引发没有明显影响。
