Svarstad E, Willassen Y, Iversen B M
Medisinsk avdeling, Haukeland sykehus, Bergen.
Tidsskr Nor Laegeforen. 1993 May 20;113(13):1589-91.
Malnutrition and low serum albumin values predict increased mortality in uremic patients. Infrared interactance represents a novel approach to the estimation of body composition. We have examined total body fat, body water and fat-free weight in our male haemodialysis (n = 24) and peritoneal dialysis (n = 17) patients. There were no differences between the groups in a cross-sectional study. A longitudinal study showed a significant increase of total body fat (%) in the peritoneal dialysis patients after five months (mean values +/- SEM) (from 19.8 +/- 2.3 to 22.6 +/- 2.4, p < 0.05), and a significant decrease of body water (%) (from 59.9 +/- 1.5 to 58.2 +/- 1.6, p < 0.05). The difference in total body fat between the haemodialysis (n = 14) and peritoneal dialysis (n = 10) groups reached statistical significance (16.5 +/- 1.7 versus 22.6 +/- 2.4, p < 0.05). No difference was found in serum albumin. Infrared interactance has the capacity to characterize time-dependent differential changes of body composition in various dialysis modalities. Further studies are needed to describe the validity of the method for identification of patients with increasing malnutrition.
营养不良和低血清白蛋白值预示着尿毒症患者死亡率的增加。红外交互作用代表了一种估计身体成分的新方法。我们已经检测了男性血液透析患者（n = 24）和腹膜透析患者（n = 17）的全身脂肪、身体水分和去脂体重。在一项横断面研究中，两组之间没有差异。一项纵向研究显示，腹膜透析患者在五个月后全身脂肪（%）显著增加（平均值±标准误）（从19.8±2.3增至22.6±2.4，p < 0.05），而身体水分（%）显著减少（从59.9±1.5降至58.2±1.6，p < 0.05）。血液透析组（n = 14）和腹膜透析组（n = 10）之间的全身脂肪差异具有统计学意义（16.5±1.7对22.6±2.4，p < 0.05）。血清白蛋白方面未发现差异。红外交互作用有能力表征不同透析方式下身体成分随时间的差异变化。需要进一步研究来描述该方法在识别营养不良加重患者方面的有效性。
