Isobe K, Aoki K, Ohno S
Department of Ophthalmology, Yokohama City University School of Medicine, Japan.
Nippon Ganka Gakkai Zasshi. 1993 May;97(5):610-3.
We compared the serum antibody titers against adenoviruses of pair sera and the identification of isolated adenovirus from 17 patients with acute conjunctivitis. Isolated adenoviruses were Ad3 in ten cases, Ad8 in four cases, Ad37 in two cases, and Ad4 in one case. Among these cases, eleven cases showed identical results in a neutralization test. In one patient from whom Ad3 was isolated, no neutralizing antibody was found. In 3 patients from whom Ad8 or Ad37 was isolated, there were discrepancies between serological results of the neutralization test or the haemagglutination inhibition test, and viral isolation. Antibody titers against adenoviruses subgenus D, such as Ad8, 19 and 37 were increased not only for the isolated serotypes, but also for other serotypes of this subgenous.
我们比较了17例急性结膜炎患者配对血清针对腺病毒的血清抗体滴度，并对分离出的腺病毒进行了鉴定。分离出的腺病毒中，10例为Ad3型，4例为Ad8型，2例为Ad37型，1例为Ad4型。在这些病例中，11例在中和试验中结果相同。在1例分离出Ad3的患者中，未发现中和抗体。在3例分离出Ad8或Ad37的患者中，中和试验或血凝抑制试验的血清学结果与病毒分离结果存在差异。针对D亚属腺病毒（如Ad8、19和37）的抗体滴度不仅针对分离出的血清型有所升高，而且针对该亚属的其他血清型也有所升高。
