Schweinfurth J M, Johnson J T, Weissman J
Department of Otolaryngology, University of Pittsburgh School of Medicine, PA.
Am J Otolaryngol. 1993 May-Jun;14(3):168-74. doi: 10.1016/0196-0709(93)90025-3.
The jugular foramen (Vernet) syndrome with neuropathy of cranial nerves IX-XI is more commonly due to metastatic lesions than primary neoplasms. Hypoglossal nerve involvement is referred to as the Collet Sicard variant of the jugular foramen syndrome.
We report an elderly man who presents with dysphagia, dysarthria, hoarseness, and a 12-pound weight loss. Examination demonstrated paralysis of the right vagus and hypoglossal nerve. Communication and collaboration with the radiologist resulted in identification of the lesion. Computed tomographic (CT) guided needle aspiration confirmed metastatic melanoma.
The onset of cranial neuropathy may allow the site of lesion to be predicted based on knowledge of the cranial base and neural anatomy. Diagnostic evaluation is tailored to evaluate the area in question. Active, multidisciplinary collaboration is essential for success.
伴有第九至十一对脑神经病变的颈静脉孔（韦尔内）综合征更常见于转移性病变而非原发性肿瘤。舌下神经受累被称为颈静脉孔综合征的科莱 - 西卡尔变异型。
我们报告了一名老年男性，他出现吞咽困难、构音障碍、声音嘶哑以及体重减轻12磅的症状。检查发现右侧迷走神经和舌下神经麻痹。与放射科医生沟通协作后确定了病变部位。计算机断层扫描（CT）引导下针吸活检确诊为转移性黑色素瘤。
根据颅底和神经解剖学知识，颅神经病变的起病情况可能有助于预测病变部位。诊断评估需针对相关区域进行。积极的多学科协作对于成功诊断至关重要。
