Seitz S, Syed Ali S, Strödter D
Institute of Anatomy and Cytobiology, Giessen, Germany.
Ann Anat. 1993 Jun;175(3):285-9. doi: 10.1016/s0940-9602(11)80020-8.
The effects of chronic streptozotozin-induced diabetes mellitus on the angioarchitecture of the heart in male Wistar rats were studied with the use of cast preparations and scanning electron microscopy. The following results were obtained in normal rats. Epicardial arteries branch obliquely and run parallel to the outer surface of the heart. Arterioles emerging from these arteries run in different directions. They show a fold-like structure equipped with a prearteriole sphincter. The capillaries in the myocardium form a net-like architecture with many H-like and Y-like anastomoses. Venous capillaries run directly into small veins at right angles while venules converge to form small veins at acute angles. In rats which have been suffering from diabetes mellitus for 8 months the capillary system appears less systematically arranged. The venous system generally exhibits dilatations. Dilatations were also seen along capillaries at short distances. In rats which had had untreated diabetes mellitus for 2 months and then 6 months of insulin treatment, a dilatation of the whole venous system was seen, but there were no significant changes in the capillary system.
利用铸型标本和扫描电子显微镜研究了慢性链脲佐菌素诱导的糖尿病对雄性Wistar大鼠心脏血管结构的影响。在正常大鼠中获得了以下结果。心外膜动脉斜行分支并与心脏外表面平行走行。从这些动脉发出的小动脉向不同方向走行。它们呈现出具有动脉前括约肌的褶皱样结构。心肌中的毛细血管形成网状结构，有许多H形和Y形吻合。静脉毛细血管直角直接汇入小静脉，而小静脉以锐角汇聚形成小静脉。在患有糖尿病8个月的大鼠中，毛细血管系统的排列似乎不太规则。静脉系统普遍出现扩张。在短距离的毛细血管处也可见扩张。在未经治疗的糖尿病大鼠中，先持续2个月，然后进行6个月胰岛素治疗，可见整个静脉系统扩张，但毛细血管系统无明显变化。
