Ichiba N, Takigawa H
Department of Pediatrics, Okayama Municipal Hospital.
No To Hattatsu. 1993 Jul;25(4):322-7.
To clarify the pathogenesis of mental deterioration in epilepsy, we investigated the intelligence of right-handed epileptic children with right hemispheric dominance of language. On dichotic listening test, all 13 patients with right-handedness, 7 to 20 years of age, showed a left ear dominance suggesting right hemispheric dominance of language. Among 13 patients, 9 showed mental retardation, and 6 patients of them showed mental deterioration during the clinical course of epilepsy. Eight patients showed findings suggesting brain damage in the left hemisphere either in clinical feature, EEG or CT. A relationship was suspected between the right-hemispheric dominance of language and the epileptic focus in the left hemisphere. The usefulness of dichotic listening test was suggested both in disclosure of the brain damage and the investigation of mental retardation in childhood epilepsy.
为阐明癫痫患者智力衰退的发病机制,我们对语言功能以右侧大脑半球占优势的右利手癫痫患儿的智力进行了研究。在双耳分听测试中,13名年龄在7至20岁的右利手患者均表现出左耳优势,提示语言功能以右侧大脑半球占优势。在这13名患者中,9名存在智力发育迟缓,其中6名在癫痫临床病程中出现智力衰退。8名患者在临床特征、脑电图或计算机断层扫描中显示出左侧大脑半球有脑损伤的迹象。怀疑语言功能的右侧大脑半球优势与左侧大脑半球的癫痫病灶之间存在关联。双耳分听测试在揭示儿童癫痫的脑损伤和智力发育迟缓研究中均显示出有用性。