Ren H Y, Chen G X, Niu L D
Henan TCM College, Zhengzhou.
Zhongguo Zhong Xi Yi Jie He Za Zhi. 1993 Mar;13(3):144-6, 131-2.
Xiang-sha Warming (XSW) and Shashen Nourishing Decoction (SSN) were used in treating Yang Deficiency Syndrome (YaDS) and Yin Deficiency Syndrome (YiDS) of chronic atrophic gastritis (CAG) respectively. 121 cases with Spleen YaDS, and 29 cases with Spleen YiDS were selected. 26 and 30 specimens were taken from gastric mucosa for observation under the SEM and TEM, including 12 and 12 YaDS cases, 14 and 12 Spleen Qi Deficiency cases respectively, 2 cases of YiDS were also observed with TEM. The specimens were taken from the same site of the gastric mucosa directly under the gastroscope pre- and post-treatment. 43 patients (35.6%) with spleen YaDS and 5 cases (17.2%) in Spleen YiDS showed marked effect after 3-month treatment. It showed that the effect in Spleen YaDS was better than YiDS. The XSW was superior than that of SSN. The effects were related to the syndromes and the degrees of pathologic change. This showed that the recipe could somewhat reverse and restore the abnormal glands of gastric mucosa.
香砂温胃方（XSW）和沙参养胃汤（SSN）分别用于治疗慢性萎缩性胃炎（CAG）的阳虚证（YaDS）和阴虚证（YiDS）。选取121例脾阳虚证患者和29例脾阴虚证患者。分别从胃黏膜取26份和30份标本进行扫描电镜（SEM）和透射电镜（TEM）观察，其中阳虚证病例各12份，脾气虚证病例分别为14份和12份，2例阴虚证患者也进行了透射电镜观察。标本于治疗前后在胃镜直视下从胃黏膜同一部位获取。3个月治疗后，43例（35.6%）脾阳虚证患者和5例（17.2%）脾阴虚证患者显效。结果显示脾阳虚证疗效优于脾阴虚证。香砂温胃方疗效优于沙参养胃汤。疗效与证候及病理改变程度有关。这表明该方剂在一定程度上可逆转和恢复胃黏膜异常腺体。
