Tesarik J, Thébault A
Center for Reproductive Biology and Medicine, American Hospital of Paris, Neuilly sur Seine, France.
Fertil Steril. 1993 Aug;60(2):369-71. doi: 10.1016/s0015-0282(16)56115-9.
A case of an isolated impairment of the ability of acrosome-reacted spermatozoa to fuse with the oocyte is reported. This impairment was associated with fertilization failure after subzonal sperm insertion even though elevated numbers of spermatozoa were inserted per oocyte. This observation shows the need for further studies into the relationship between the acrosome reaction and the sperm-oocyte fusion to better understand the advantages and the limitations of subzonal sperm insertion in different types of sperm pathology.
报道了一例顶体反应的精子与卵母细胞融合能力单独受损的病例。尽管每个卵母细胞插入的精子数量增加，但这种损伤与透明带下精子注射后的受精失败有关。这一观察结果表明，需要进一步研究顶体反应与精卵融合之间的关系，以便更好地理解在不同类型的精子病理学中透明带下精子注射的优势和局限性。
