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“血管母细胞性脑膜瘤”、血管外皮细胞瘤与小脑成血管细胞瘤的比较研究

[A comparative study of "angioblastic meningioma", hemangiopericytoma and cerebellar hemangioblastoma].

作者信息

Zhou Q, Liu K, Wang L, Yang X

出版信息

Hua Xi Yi Ke Da Xue Xue Bao. 1993 Mar;24(1):9-12.

PMID:8340101
Abstract

Forty-nine cases of the so-called "angioblastic meningioma", six cases of cerebellar hemangioblastoma, and four cases of soft tissue hemangiopericytoma were studied with HE, reticulin stainings, and immunohistochemical reaction with Vimentin, EMA, GFAP, S-100, and UEA-1 antibodies. The results showed that among the three subtypes of "angioblastic meningioma", namely, the hemangiomatous (H), the hemangioblastic (AB), and the hemangiopericytic (P) types, (1) type H belongs to true meningioma; (2) most of type P are almost identical with soft tissue hemangiopericytoma and different from true meningiomas, therefore belong to hemangiopericytoma arising from pericytes; however (3) some true meningiomas may appear as hemangiopericytoma histologically; (4) a few of AB are very similar to cerebellar hemangioblastoma and thus should be considered as supratentorial hemangioblastoma, while most of AB are still true meningiomas.

摘要

对49例所谓的“血管母细胞性脑膜瘤”、6例小脑成血管细胞瘤和4例软组织血管外皮细胞瘤进行了苏木精-伊红(HE)染色、网状纤维染色以及波形蛋白、上皮膜抗原(EMA)、胶质纤维酸性蛋白(GFAP)、S-100和荆豆凝集素-1(UEA-1)抗体的免疫组化反应研究。结果显示,在“血管母细胞性脑膜瘤”的三种亚型,即血管瘤型(H)、血管母细胞型(AB)和血管外皮细胞型(P)中,(1)H型属于真性脑膜瘤;(2)大多数P型与软组织血管外皮细胞瘤几乎相同,与真性脑膜瘤不同,因此属于源自周细胞的血管外皮细胞瘤;然而(3)一些真性脑膜瘤在组织学上可能表现为血管外皮细胞瘤;(4)少数AB型与小脑成血管细胞瘤非常相似,因此应被视为幕上成血管细胞瘤,而大多数AB型仍然是真性脑膜瘤。

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