Tsukerman G L, Krapiva G A, Kirillova I A
Byelorussian Institute for Hereditary Diseases, Minsk, Belarus.
Prenat Diagn. 1993 May;13(5):371-6. doi: 10.1002/pd.1970130509.
Duodenal stenosis associated with oesophageal atresia was diagnosed by ultrasound at 12 weeks' gestation. The diagnosis was made by recognition of a double bubble sign which was more pronounced when a vaginal transducer was used. Post-abortion autopsy confirmed the diagnosis. Oesophageal and duodenal obstruction in this case had no effect on the amount of amniotic fluid or the alpha-fetoprotein concentration since swallowing and subsequent utilization of amniotic fluid do not occur before 12 weeks of gestation.
妊娠12周时通过超声诊断出与食管闭锁相关的十二指肠狭窄。诊断依据是识别出双泡征，使用阴道探头时该征象更为明显。流产后尸检证实了诊断。在这种情况下，食管和十二指肠梗阻对羊水的量或甲胎蛋白浓度没有影响，因为在妊娠12周之前不会发生羊水的吞咽及后续利用。
