Sarti C, Tuomilehto J, Sivenius J, Kaarsalo E, Narva E V, Salmi K, Salomaa V, Torppa J
Department of Epidemiology and Health Promotion, National Public Health Institute of Helsinki, Finland.
Stroke. 1993 Aug;24(8):1140-7. doi: 10.1161/01.str.24.8.1140.
Our aim was to describe the mortality and early case-fatality rates of stroke in three geographic areas of Finland during 1983 to 1986 by means of a community-based stroke register and to estimate the accuracy of registration of stroke deaths in the official statistics compared with the FINMONICA stroke register.
Annual and average mortality and case-fatality rates of stroke were derived from data collected in the FINMONICA stroke register during 1983 to 1986. Age-specific and age-standardized rates were calculated for the three areas, and the results were compared with the official mortality statistics and with the case-fatality figures published previously in the literature for Finland and elsewhere.
Mortality from stroke in the three FINMONICA areas was between 73 and 90 per 100,000 per year among men aged 25 to 74 years and between 42 and 55 per 100,000 per year among women in the same age group. Average case-fatality was similar in the three areas and globally high: 20% to 27% in men and 24% to 28% in women. Approximately half of the fatal strokes occurred within less than 2 days from the onset of the attack, and a further 25% within the first week. Hemorrhagic strokes accounted for 54% to 81% of all fatal strokes occurring in less than 2 days among men, while among women the corresponding proportions varied in the three areas between 35% and 74%. Of cerebral infarctions, approximately 28% to 37% among men and 19% to 20% among women were fatal within less than 2 days. Although the number of fatal strokes was similar in both the FINMONICA register and official mortality statistics, only 82% to 85% of the stroke cases were common in both registers; a further 13% to 14% of the cases classified as stroke deaths in the FINMONICA register could also be found in the official mortality statistics, but the underlying cause of death was something other than stroke.
The reliability of the Finnish official mortality statistics with regard to stroke deaths is reasonably good in aggregate numbers, but at the individual level considerable discrepancies seem to occur. Mortality from stroke in Finland has not declined further after 1979 and remains high internationally. Early case-fatality of stroke also seems higher in Finland than in most other countries. We believe that both the high incidence of stroke and the severity of the attacks are contributing to mortality and case-fatality rates of stroke in Finland.
我们的目的是通过基于社区的卒中登记系统描述1983年至1986年芬兰三个地理区域的卒中死亡率和早期病死率,并评估官方统计中卒中死亡登记相对于芬兰MONICA卒中登记的准确性。
卒中的年度和平均死亡率及病死率来自于1983年至1986年芬兰MONICA卒中登记系统收集的数据。计算了三个区域的年龄别和年龄标准化率,并将结果与官方死亡率统计数据以及芬兰和其他地方先前文献中公布的病死率数据进行比较。
在25至74岁的男性中,芬兰MONICA三个区域的卒中死亡率为每年每10万人73至90例,同年龄组女性为每年每10万人42至55例。三个区域的平均病死率相似且总体较高:男性为20%至27%,女性为24%至28%。约一半的致命性卒中发生在发病后不到2天内,另有25%发生在第一周内。出血性卒中在男性发病后不到2天内发生的所有致命性卒中中占54%至81%,而在女性中,三个区域的相应比例在35%至74%之间变化。在脑梗死中,男性约28%至37%、女性约19%至20%在发病后不到2天内死亡。虽然芬兰MONICA登记系统和官方死亡率统计中的致命性卒中数量相似,但两个登记系统中只有82%至85%的卒中病例是相同的;在芬兰MONICA登记系统中被归类为卒中死亡的病例,另有13%至14%也可在官方死亡率统计中找到,但死亡的根本原因不是卒中。
芬兰官方死亡率统计中关于卒中死亡的数据,总体数量上可靠性较好,但在个体层面似乎存在相当大的差异。1979年后芬兰的卒中死亡率没有进一步下降,在国际上仍然很高。芬兰卒中的早期病死率似乎也高于大多数其他国家。我们认为,卒中的高发病率和发作的严重性共同导致了芬兰卒中的死亡率和病死率。