[A prospective and randomized study of the complete response, index of recurrences and progression in superficial bladder carcinoma treated with mitomycin C alone versus mitomycin C and BCG alternatively].

The results of a comparative randomized study on intravesical chemoprophylaxis are presented. The study comprised 66 patients; one group of 29 patients received mitomycin C alone, while another group of 37 patients received mitomycin C and alternating BCG therapy. This latter treatment modality was found to achieve a slightly higher complete response rate and a much lower tumor progression rate. Although these results were not statistically significant (p > 0.05), they indicate that if the study were comprised of a larger series, the combined modality may be shown to achieve better results than the other modalities currently used.