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大鼠外周酯酶:经典诱导剂的作用

Peripheral esterases in the rat: effects of classical inducers.

作者信息

McCracken N W, Blain P G, Williams F M

机构信息

Toxicology Unit, Medical School, Newcastle University, UK.

出版信息

Chem Biol Interact. 1993 Jun;87(1-3):183-5. doi: 10.1016/0009-2797(93)90041-v.

DOI:10.1016/0009-2797(93)90041-v
PMID:8343974
Abstract

Liver microsomal paraoxonase, aryl esterase and fluazifop butyl esterase (carboxylesterase) were induced by pretreatment of rat with phenobarbitone but not by beta-naphthoflavone or clofibric acid. In the extrahepatic tissues lung cytosolicfluazifop butyl and phenylacetate esterase were induced.

摘要

用苯巴比妥预处理大鼠可诱导肝脏微粒体对氧磷酶、芳基酯酶和氟吡甲禾灵丁酯酶(羧酸酯酶),但β-萘黄酮或氯贝酸不能诱导。在肝外组织中,肺胞质中的氟吡甲禾灵丁酯酶和苯乙酸酯酶被诱导。

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Peripheral esterases in the rat: effects of classical inducers.大鼠外周酯酶:经典诱导剂的作用
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