Allibone R O, Hoffman J, Gosney J R, Helliwell T R
Department of Histopathology, Royal Devon and Exeter Hospital, Liverpool, UK.
Histopathology. 1993 May;22(5):475-80. doi: 10.1111/j.1365-2559.1993.tb00161.x.
We report two patients with ileal carcinoid tumours which were associated with polyps due to mucosal granulation tissue proliferation. In both cases the tumours had extensively infiltrated the small bowel wall and mesentery, and one had hepatic metastases. The mucosal surface of each specimen showed numerous, pale brown, sessile polyps which were restricted to the intestinal segment involved by carcinoid tumour, although not always closely related to neoplastic cells. The polyps were formed by the proliferation of capillaries, smooth muscle cells and myofibroblasts as demonstrated by immunohistochemistry and electronmicroscopy.
我们报告了两名患有回肠类癌肿瘤的患者，这些肿瘤与因黏膜肉芽组织增生而形成的息肉相关。在这两个病例中，肿瘤均已广泛浸润小肠壁和肠系膜，其中一例有肝转移。每个标本的黏膜表面都有许多浅棕色的无蒂息肉，这些息肉局限于类癌肿瘤累及的肠段，尽管并不总是与肿瘤细胞紧密相关。免疫组织化学和电子显微镜检查显示，息肉由毛细血管、平滑肌细胞和成肌纤维细胞的增殖形成。
