Lopez A E, Padron O F, Patsias G, Politano V A
Department of Urology, University of Miami School of Medicine, Florida.
J Urol. 1993 Sep;150(3):856-8. doi: 10.1016/s0022-5347(17)35632-x.
We present our results with the use of transurethral injection of polytetrafluoroethylene (Teflon) in 128 female patients with moderate to severe urinary incontinence from 1964 to 1991. Of the patients 60% had undergone previous surgical treatment for the incontinence. The etiologies included stress incontinence, neurogenic bladder, congenital anomalies, trauma and others. More than 73% of the patients improved (54.3% were totally dry). The failure rate was 27%. Complications were minimal. Urinary tract infection and temporary urinary retention occurred in 7 and 6 patients, respectively. Mean followup was 31 months. This study demonstrates that transurethral polytetrafluoroethylene injection is a useful treatment of moderate to severe urinary incontinence in female patients. Polytetrafluoroethylene is particularly useful for patients with failed previous incontinence procedures and poor surgical candidates. Failures are more likely in patients with periurethral fibrosis secondary to a previous urethral operation.
我们报告了1964年至1991年间对128例中重度尿失禁女性患者采用经尿道注射聚四氟乙烯（特氟龙）的治疗结果。这些患者中60%曾因尿失禁接受过手术治疗。病因包括压力性尿失禁、神经源性膀胱、先天性异常、创伤等。超过73%的患者病情改善（54.3%完全无尿失禁）。失败率为27%。并发症极少。分别有7例和6例患者发生尿路感染和暂时性尿潴留。平均随访31个月。本研究表明，经尿道注射聚四氟乙烯是治疗女性中重度尿失禁的一种有效方法。聚四氟乙烯对既往尿失禁手术失败且手术条件不佳的患者尤为有用。既往尿道手术继发尿道周围纤维化的患者更易出现治疗失败。
