Roach M B, Switters D M, Stone A R
Department of Urology, University of California, Davis, Sacramento.
J Urol. 1993 Sep;150(3):944-7. doi: 10.1016/s0022-5347(17)35657-4.
A total of 43 infants with spina bifida was evaluated with a standard simplified urodynamic technique to determine whether bladder behavior altered with development and the optimal timing for urodynamic testing. Using urodynamic evaluation plus renal ultrasound and voiding cystourethrography the patients were divided into 2 groups: 1) those with a favorable prognosis and 2) those with an unfavorable prognosis. Only 55% of the initial urodynamic studies were predictive of future clinical course. The patients who worsened generally did so in the first 6 months of life. Of the patients initially believed to have an unfavorable prognosis 86% improved or stabilized with therapy. Urodynamic testing appears to be an important adjunct at 6-month intervals in infancy and early childhood as bladder behavior continues to evolve.
采用标准简化尿动力学技术对43例脊柱裂婴儿进行评估，以确定膀胱功能是否随发育而改变以及尿动力学检查的最佳时机。通过尿动力学评估、肾脏超声检查和排尿性膀胱尿道造影，将患者分为两组：1）预后良好组；2）预后不良组。最初的尿动力学研究中只有55%能预测未来的临床病程。病情恶化的患者通常在出生后的前6个月内出现恶化。最初被认为预后不良的患者中，86%经治疗后病情改善或稳定。由于婴儿期和幼儿期膀胱功能持续演变，尿动力学检查似乎是每6个月进行一次的重要辅助检查。
