非吸烟者肺泡内巨噬细胞数量随年龄增长而增加。
Age related increase in the intra-alveolar macrophage population of non-smokers.
作者信息
Wallace W A, Gillooly M, Lamb D
机构信息
Department of Pathology, Edinburgh University Medical School.
出版信息
Thorax. 1993 Jun;48(6):668-9. doi: 10.1136/thx.48.6.668.
Abstract
The alveolar macrophage population is higher in smokers than in non-smokers. An age related increase in the alveolar macrophage number in the lungs of non-smokers has been found, whether expressed per unit lung volume or per unit lung surface area.
摘要
吸烟者的肺泡巨噬细胞数量高于不吸烟者。研究发现，无论以单位肺容积还是单位肺表面积计算，不吸烟者肺部的肺泡巨噬细胞数量会随着年龄增长而增加。
相似文献
1
Age related increase in the intra-alveolar macrophage population of non-smokers.非吸烟者肺泡内巨噬细胞数量随年龄增长而增加。
Thorax. 1993 Jun;48(6):668-9. doi: 10.1136/thx.48.6.668.
2
Intra-alveolar macrophage numbers in current smokers and non-smokers: a morphometric study of tissue sections.当前吸烟者与非吸烟者的肺泡内巨噬细胞数量：组织切片的形态计量学研究
Thorax. 1992 Jun;47(6):437-40. doi: 10.1136/thx.47.6.437.
3
Collagen content of alveolar wall tissue in emphysematous and non-emphysematous lungs.肺气肿和非肺气肿肺组织中肺泡壁组织的胶原蛋白含量。
Thorax. 1994 Apr;49(4):319-26. doi: 10.1136/thx.49.4.319.
4
Smoking impairs alveolar macrophage activation after inert dust exposure.吸烟会削弱接触惰性粉尘后肺泡巨噬细胞的激活。
Toxicol Lett. 1996 Nov;88(1-3):131-7. doi: 10.1016/0378-4274(96)03728-9.
5
6
p21(CIP1/WAF1) and the immunologic fate of macrophages in smokers: at the crossroad between proliferation, survival, and death.p21（CIP1/WAF1）与吸烟者巨噬细胞的免疫命运：处于增殖、存活和死亡的十字路口
Am J Respir Crit Care Med. 2002 Sep 1;166(5):637-8. doi: 10.1164/rccm.2205026.
7
Alveolar inflammation and its relation to emphysema in smokers.吸烟者的肺泡炎症及其与肺气肿的关系。
Am J Respir Crit Care Med. 1995 Nov;152(5 Pt 1):1666-72. doi: 10.1164/ajrccm.152.5.7582312.
8
Smoking alters alveolar macrophage recognition and phagocytic ability: implications in chronic obstructive pulmonary disease.吸烟改变肺泡巨噬细胞的识别和吞噬能力：对慢性阻塞性肺疾病的影响。
Am J Respir Cell Mol Biol. 2007 Dec;37(6):748-55. doi: 10.1165/rcmb.2007-0025OC. Epub 2007 Jul 13.
9
Phagolysosomal pH in alveolar macrophages from smokers and non-smokers.吸烟者和非吸烟者肺泡巨噬细胞中吞噬溶酶体的pH值。
Hum Exp Toxicol. 1994 Mar;13(3):175-9. doi: 10.1177/096032719401300307.
10
Reduced DNA methylation of sphingosine-1 phosphate receptor 5 in alveolar macrophages in COPD: A potential link to failed efferocytosis.慢性阻塞性肺疾病患者肺泡巨噬细胞中鞘氨醇-1-磷酸受体5的DNA甲基化降低：与吞噬功能障碍的潜在联系
Respirology. 2017 Feb;22(2):315-321. doi: 10.1111/resp.12949. Epub 2016 Nov 20.
引用本文的文献
1
Comparison of respiratory muscle activities and cardiovascular function during different breathing types in healthy adults: Costal breathing, flow incentive spirometry, and volume incentive spirometry.健康成年人不同呼吸类型下呼吸肌活动与心血管功能的比较：肋式呼吸、流量激励肺活量测定法和容量激励肺活量测定法。
PLoS One. 2025 Jul 28;20(7):e0328739. doi: 10.1371/journal.pone.0328739. eCollection 2025.
2
Functional, transcriptional, and microbial shifts associated with healthy pulmonary aging in rhesus macaques.与食蟹猴肺部健康衰老相关的功能、转录和微生物变化。
Cell Rep. 2022 Apr 19;39(3):110725. doi: 10.1016/j.celrep.2022.110725.
3
ISM1 protects lung homeostasis via cell-surface GRP78-mediated alveolar macrophage apoptosis.ISM1 通过细胞表面 GRP78 介导的肺泡巨噬细胞凋亡来保护肺内稳态。
Proc Natl Acad Sci U S A. 2022 Jan 25;119(4). doi: 10.1073/pnas.2019161119.
4
Modeling Early Stages of Bone and Joint Infections Dynamics in Humans: A Multi-Agent, Multi-System Based Model.人类骨骼和关节感染动力学早期阶段建模：一种基于多智能体、多系统的模型。
Front Mol Biosci. 2020 Mar 12;7:26. doi: 10.3389/fmolb.2020.00026. eCollection 2020.
5
Localization of Macrophages in the Human Lung via Design-based Stereology.基于设计的体视学方法定位人肺中的巨噬细胞。
Am J Respir Crit Care Med. 2020 May 15;201(10):1209-1217. doi: 10.1164/rccm.201911-2105OC.
6
Redox mechanisms in age-related lung fibrosis.年龄相关性肺纤维化中的氧化还原机制。
Redox Biol. 2016 Oct;9:67-76. doi: 10.1016/j.redox.2016.06.005. Epub 2016 Jun 25.
本文引用的文献
1
Airspace size in lungs of lifelong non-smokers: effect of age and sex.终生不吸烟者肺部的气腔大小：年龄和性别的影响。
Thorax. 1993 Jan;48(1):39-43. doi: 10.1136/thx.48.1.39.
2
Age influence on the immune system.年龄对免疫系统的影响。
Adv Immunol. 1980;29:287-330. doi: 10.1016/s0065-2776(08)60047-4.
3
The immune status of healthy centenarians.健康百岁老人的免疫状态。
J Am Geriatr Soc. 1984 Apr;32(4):274-81. doi: 10.1111/j.1532-5415.1984.tb02021.x.
4
Proliferating cell nuclear antigen (PCNA) immunolocalization in paraffin sections: an index of cell proliferation with evidence of deregulated expression in some neoplasms.石蜡切片中增殖细胞核抗原（PCNA）的免疫定位：一种细胞增殖指标，在某些肿瘤中存在表达失调的证据。
J Pathol. 1990 Dec;162(4):285-94. doi: 10.1002/path.1711620403.
5
New automated technique for assessing emphysema on histological sections.用于在组织学切片上评估肺气肿的新型自动化技术。
J Clin Pathol. 1991 Dec;44(12):1007-11. doi: 10.1136/jcp.44.12.1007.
6
Intra-alveolar macrophage numbers in current smokers and non-smokers: a morphometric study of tissue sections.当前吸烟者与非吸烟者的肺泡内巨噬细胞数量：组织切片的形态计量学研究
Thorax. 1992 Jun;47(6):437-40. doi: 10.1136/thx.47.6.437.
Zotero 插件