Mätz K, Gerhards H, Heider H J, Drommer W
Abteilung für Elektronenmikroskopie, Tierärztlichen Hochschule Hannover.
Tierarztl Prax. 1993 Jun;21(3):225-32.
Bilateral blindness was diagnosed in a 5-year-old Hanoverian gelding presented for evaluation of a corneal opacity in one eye. About 12 months prior to the examination, the gelding had fallen head over, hitting his head and the cornea. Clinical and electroretinographic findings as well as pathohistologic and ultrastructural lesions of both eyes including the optic nerves are presented. Ophthalmoscopically visible pigment disruption of the non-tapetal fundus adjacent to the optic discs correlated morphologically with foci of degeneration and atrophy of the retina, whereas ophthalmoscopically visible accumulation of pigment was morphologically characterized by hypertrophy of the pigment epithelium, increased intracellular pigment accumulation and by migration of pigment cells into the inner lamina of the retina. Severe atrophy of the retinal neuronal layer was linked to traumatic optic nerve degeneration.
一匹5岁的汉诺威种公马因一只眼睛角膜混浊前来评估,被诊断为双侧失明。在检查前约12个月,这匹马头部着地摔倒,撞到了头部和角膜。本文展示了双眼包括视神经的临床、视网膜电图检查结果以及病理组织学和超微结构病变。眼底镜检查可见视盘附近非视锥视杆细胞层色素紊乱,在形态学上与视网膜变性和萎缩灶相关,而眼底镜检查可见的色素积聚在形态学上表现为色素上皮肥大、细胞内色素积聚增加以及色素细胞迁移至视网膜内层。视网膜神经层的严重萎缩与外伤性视神经变性有关。