Akiyama T
Dept. of Oncogene Research, Osaka University.
Gan To Kagaku Ryoho. 1993 Aug;20(10):1429-34.
Inactivation of antioncogenes result in the generation of tumor cells. Recent progress in molecular biology of antioncogenes enabled us to study the function of the products of RB, WT, p53, NF1, DCC, APC and MCC genes. Analyses of the function of these proteins will give us an insight into the mechanisms of cell transformation.
抗癌基因的失活会导致肿瘤细胞的产生。抗癌基因分子生物学的最新进展使我们能够研究RB、WT、p53、NF1、DCC、APC和MCC基因产物的功能。对这些蛋白质功能的分析将使我们深入了解细胞转化的机制。