新生儿血压和心率的周期性变化。
Cyclical variation of blood pressure and heart rate in neonates.
作者信息
Cunningham S, Deere S, McIntosh N
机构信息
Neonatal Unit, Simpson Memorial Maternity Pavilion, Edinburgh.
出版信息
Arch Dis Child. 1993 Jul;69(1 Spec No):64-7. doi: 10.1136/adc.69.1_spec_no.64.
Using a computerised physiological monitoring system a cyclical variation in blood pressure (waves), with associated changes in heart rate and transcutaneous oxygen, was observed. Twenty five episodes were seen in 10 neonates, with a median gestation of 33 weeks (range 28-42 weeks). Eight neonates had an asphyxial injury. Blood pressure waves had a mean (SD) amplitude of 11.6 (5.6) mm Hg with a mean wavelength of 9.0 (5.2) minutes. Both amplitude and frequency were independent of gestation. In neonates of less than 34 weeks an inverse phase relation existed between heart rate and blood pressure waves (blood pressure rose as heart rate fell); in infants with a gestation greater than 34 weeks a direct phase relationship occurred (blood pressure and heart rate rose together). It is postulated that hypertensive blood pressure waves may cause or exacerbate cerebral pathology in neonates with a pressure passive cerebral circulation.
使用计算机化生理监测系统观察到血压呈周期性变化（波动），同时伴有心率和经皮氧含量的相关变化。在10例新生儿中观察到25次发作，中位胎龄为33周（范围28 - 42周）。8例新生儿有窒息损伤。血压波动的平均（标准差）幅度为11.6（5.6）mmHg，平均波长为9.0（5.2）分钟。幅度和频率均与胎龄无关。在胎龄小于34周的新生儿中，心率与血压波动呈反相位关系（心率下降时血压上升）；在胎龄大于34周的婴儿中，呈正相位关系（血压和心率同时上升）。据推测，高血压性血压波动可能会导致或加重脑循环压力被动的新生儿的脑部病变。
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