Macchiarini P, Chapelier A, Lenot B, Cerrina J, Dartevelle P
Department of Thoracic and Vascular Surgery and Heart-Lung Transplantation, Hôpital Marie-Lannelongue, Paris-Sud University, Plessis Robinson, France.
Eur J Cardiothorac Surg. 1993;7(6):300-5. doi: 10.1016/1010-7940(93)90171-7.
Between 1981 and June 1992, 26 consecutive patients with a postintubation subglottic stenosis (21 circumferential, 2 anterolateral) underwent the Pearson operation. Subglottic stenosis resulted from a complication of mechanical ventilation with endotracheal intubation with (n = 14) or without (n = 12) tracheostomy (median placement: 25 days). One patient had an associated laryngopharyngeal and tracheoesophageal fistula. Overall, the upper limit of the stenoses lay 1.8 +/- 0.3 cm below the vocal cords, falling in the range of 1 to 2 cm in 88% of patients; they measured 2.9 +/- 0.8 cm in length and the diameter at the level of the maximum stenotic process was 0.5 +/- 0.1 cm. Operations were performed without dissection of the recurrent nerves and plicature of the membranous trachea. Because of scarred mucosa at a higher level, one vertical section of the posterior cricoid plate with interposition of autogenous costal cartilage and 2 subtotal cricoid plate resections with stenting were necessary. The mean length of resection was 3.6 +/- 0.8 cm (range: 2-5 cm) and 88% of them ranged within 2.8 and 5 cm. Twelve thyrohyoid and 3 supralaryngeal releases were performed. Six patients required postoperative tracheostomy, but all were extubated within 24 h. Good results were obtained in 24 (96%) surviving patients; 1 failure and 1 postoperative death (sudden myocardial infarction) occurred. The results confirm that the Pearson operation is an adequate treatment for subglottic stenosis extending up to 1 cm below the vocal cords and measuring up to 6 cm in length. Dissection of both the recurrent nerves, plicature of the membranous trachea, postoperative decompressive tracheostomy and stenting are not necessary.
1981年至1992年6月期间,连续26例气管插管后声门下狭窄患者(21例为环状狭窄,2例为前外侧狭窄)接受了皮尔逊手术。声门下狭窄是由气管插管机械通气并发症引起的,其中14例伴有气管切开术,12例未行气管切开术(中位置管时间:25天)。1例患者伴有喉咽和气管食管瘘。总体而言,狭窄的上限位于声带下方1.8±0.3 cm处,88%的患者在此范围为1至2 cm;狭窄长度为2.9±0.8 cm,最大狭窄处的直径为0.5±0.1 cm。手术未进行喉返神经解剖和气管膜部折叠。由于较高水平的黏膜瘢痕化,1例需要行环状软骨后板垂直切开并植入自体肋软骨,2例需要行环状软骨板次全切除并置入支架。平均切除长度为3.6±0.8 cm(范围:2 - 5 cm),88%的切除长度在2.8至5 cm之间。进行了12例甲状舌骨松解术和3例喉上松解术。6例患者术后需要气管切开,但均在24小时内拔管。24例存活患者(96%)取得了良好效果;发生1例手术失败和1例术后死亡(突发心肌梗死)。结果证实,皮尔逊手术是治疗声门下狭窄的一种合适方法,该狭窄位于声带下方达1 cm,长度达6 cm。无需解剖双侧喉返神经、气管膜部折叠、术后减压性气管切开及置入支架。