儿童免疫性血小板减少性紫癜患者短期应用重组α-2b干扰素治疗后血小板计数增加
Increase in platelet count following short course therapy with recombinant alpha-2b-interferon in immune thrombocytopenic purpura in childhood.
作者信息
Behrenbeck U, Riedel F, Rieger C H
机构信息
Children's Hospital, Philipp's University, Marburg, Germany.
出版信息
Pediatr Allergy Immunol. 1993 Feb;4(1):10-2. doi: 10.1111/j.1399-3038.1993.tb00058.x.
Abstract
Two boys, aged three and seven years with immune thrombocytopenic purpura continued to show platelet counts below 20,000/mm3 inspite of treatment with high dose gammaglobulin and steroids. Alpha-2b-interferon injections were followed by normalisation of platelet counts in both patients. No side effects were seen. Alpha-interferon may be a safe and effective treatment for childhood-ITP.
摘要
两名患有免疫性血小板减少性紫癜的男孩，年龄分别为3岁和7岁，尽管接受了大剂量丙种球蛋白和类固醇治疗，血小板计数仍持续低于20,000/mm³。两名患者在注射α-2b干扰素后血小板计数均恢复正常，且未观察到副作用。α-干扰素可能是治疗儿童免疫性血小板减少性紫癜的一种安全有效的方法。
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