Antecol D H, Jugdutt B I
Department of Medicine, University of Alberta, Edmonton.
Can J Cardiol. 1993 Jun;9(5):428-32.
A patient with extensive myocardial infarction, evidence of early ventricular remodelling, regional left ventricular (LV) dilation and aneurysm formation developed recurrent ventricular tachyarrhythmias and episodes of sudden death. The patient finally died 24 days post infarction despite effective anti-remodelling therapy and appropriate anti-failure and anti-arrhythmic therapies. Remarkable findings at autopsy included normal LV size and a small LV apical aneurysm despite as much as 52% LV necrosis and further right ventricular necrosis. The case underscores the need for aggressive early infarct-limiting therapy to prevent early remodelling, LV aneurysm and possibly fatal ventricular tachyarrhythmias.
一名患有广泛心肌梗死、存在早期心室重构证据、局部左心室（LV）扩张和动脉瘤形成的患者出现了复发性室性心律失常和猝死发作。尽管进行了有效的抗重构治疗以及适当的抗心力衰竭和抗心律失常治疗，但该患者最终在梗死24天后死亡。尸检时的显著发现包括左心室大小正常以及一个小的左心室心尖部动脉瘤，尽管左心室坏死达52%，且右心室进一步坏死。该病例强调了积极进行早期梗死限制治疗以预防早期重构、左心室动脉瘤以及可能致命的室性心律失常的必要性。
