Layfield L J, Chrischilles E A, Cohen M B, Bottles K
Department of Pathology, Duke University Medical Center, Durham, NC 27705.
Cancer. 1993 Sep 1;72(5):1642-51. doi: 10.1002/1097-0142(19930901)72:5<1642::aid-cncr2820720525>3.0.co;2-8.
Traditionally, open biopsy has been considered the optimal procedure for the diagnosis of breast nodules. Fine-needle aspiration biopsy (FNAB) has been proposed as an alternate method for the diagnosis of many palpable breast lesions.
The authors compared the diagnostic utility of open biopsy and FNAB using decision tree and cost-effectiveness analyses.
When compared with two-step excisional biopsy, FNAB achieved a savings of over $700 at the cost of 0.1% decrease in 10-year overall survival.
These data indicate FNAB to be a reasonable alternative to open biopsy for the diagnosis of palpable breast lesions in many patients.
传统上，开放式活检一直被认为是诊断乳腺结节的最佳方法。细针穿刺活检（FNAB）已被提议作为诊断许多可触及乳腺病变的替代方法。
作者使用决策树和成本效益分析比较了开放式活检和FNAB的诊断效用。
与两步切除活检相比，FNAB节省了超过700美元，但代价是10年总生存率下降了0.1%。
这些数据表明，对于许多患者，FNAB是诊断可触及乳腺病变的开放式活检的合理替代方法。
