Salzman J P, Salzman C, Wolfson A N, Albanese M, Looper J, Ostacher M, Schwartz J, Chinman G, Land W, Miyawaki E
Department of Psychiatry, Harvard Medical School, Boston, MA.
Compr Psychiatry. 1993 Jul-Aug;34(4):254-7. doi: 10.1016/0010-440x(93)90007-q.
Childhood abuse has been implicated as a leading factor in the development of borderline personality disorder (BPD). Data in this report, drawn from an ongoing study of the therapeutic effect of fluoxetine in BPD patients, were gathered in an attempt to replicate previous findings indicating a history of physical abuse in 71% and sexual abuse in 67% of adult BPD subjects. Thirty-one subjects for a study of the pharmacological treatment of BPD or BPD traits met criteria for the study. Those who had been previously hospitalized for a psychiatric disorder, who had recently been suicidal, or who had recent histories of self-mutilation were excluded. Specific information about childhood abuse was gathered using questions from a previous study of abuse histories in BPD patients. All subjects were then interviewed in greater depth regarding past experiences of abuse as part of the ongoing study of the relationship of childhood attachment experience and adult psychopathology. Six of 31 subjects (19.4%) reported a definite history of childhood physical and/or sexual abuse. Four of these subjects met criteria for full BPD, and two met criteria for BPD traits. Three of 31 subjects reported a history of physical abuse (9.7%); five reported a history of sexual abuse (16.1%). Two of the six who reported abuse reported both physical and sexual abuse. A history of childhood abuse is not necessarily linked to the development of BPD or BPD traits in all individuals. The following hypothesis is suggested: BPD may represent a spectrum of symptomatic severity.(ABSTRACT TRUNCATED AT 250 WORDS)
童年期受虐被认为是边缘性人格障碍(BPD)发展的一个主要因素。本报告中的数据来自一项正在进行的关于氟西汀对BPD患者治疗效果的研究,收集这些数据是为了重复之前的研究结果,即71%的成年BPD患者有身体虐待史,67%有性虐待史。31名参与BPD或BPD特质药物治疗研究的受试者符合研究标准。那些曾因精神疾病住院、近期有自杀行为或近期有自残史的人被排除在外。使用之前一项关于BPD患者虐待史研究中的问题收集了有关童年期受虐的具体信息。然后,作为正在进行的关于童年依恋经历与成人精神病理学关系研究的一部分,对所有受试者就过去的受虐经历进行了更深入的访谈。31名受试者中有6名(19.4%)报告有明确的童年期身体和/或性虐待史。其中4名受试者符合完全BPD的标准,2名符合BPD特质的标准。31名受试者中有3名报告有身体虐待史(9.7%);5名报告有性虐待史(16.1%)。报告受虐的6人中,有2人同时报告了身体虐待和性虐待。童年期受虐史并不一定与所有个体的BPD或BPD特质发展相关。提出了以下假设:BPD可能代表一系列症状严重程度。(摘要截选于250字)