Malaval T, Li V, Jang G, Martins Ramos J, Mézin P, Fournet J, Hostein J
Service de Gastroentérologie et d'Hépatologie, Hôpital Albert-Michallon, Grenoble.
Gastroenterol Clin Biol. 1993;17(5):386-90.
The authors report the case of a 61-year old patient with a Churg-Strauss syndrome revealed by abdominal pain. Investigations showed a diffuse inflammatory digestive tract involvement, documented by endoscopy associated with protein-losing enteropathy. Deep rectal biopsy revealed vasculitis in an otherwise macroscopically normal rectum. Faced with acute and life-threatening course of disease, emergency medical treatment with steroids and cyclophosphamide led to rapid regression of clinical, biological and radiological abnormalities.
作者报告了一例61岁因腹痛而被诊断为变应性肉芽肿性血管炎综合征的患者。检查显示存在弥漫性炎症性消化道受累,经内镜检查并结合蛋白丢失性肠病得以证实。直肠深层活检显示,在肉眼外观正常的直肠中存在血管炎。面对急性且危及生命的病程,使用类固醇和环磷酰胺进行紧急药物治疗后,临床、生物学及影像学异常迅速消退。