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Criteria for selection of patients for medical treatment (chenodeoxycholic acid therapy) of gallstones.

作者信息

Bruusgaard A, Malver E, Pedersen L R, Schlichting P, Sylvest J

出版信息

Scand J Gastroenterol. 1977;12(1):97-102.

PMID:834976
Abstract

With the introduction of medical treatment (chenodeoxycholic acid therapy) of cholesterol gallstones, the prediction of the gallstone type, cholesterol--non-cholesterol stones, (i.e. cholesterol predominating or not), has become important. In 24 consecutive patients admitted for surgery because of gallstones, the value of various criteria for differentiation between the two types of stones was assessed. It is concluded that the combined requirements of radiolucency of the stones and a cholesterol saturation index in duodenal bile above 1.00 constitutes a fairly reliable method for selection of patients for dissolution therapy with chenodeoxycholic acid.

摘要

相似文献

1
Criteria for selection of patients for medical treatment (chenodeoxycholic acid therapy) of gallstones.
Scand J Gastroenterol. 1977;12(1):97-102.
2
Changes of bile acid and lipid composition in blood and bile in the clinical course after the initiation of cheno- and ursodeoxycholic acid therapy in patients with cholesterol gallstones.胆固醇结石患者开始使用鹅去氧胆酸和熊去氧胆酸治疗后临床过程中血液和胆汁中胆汁酸及脂质成分的变化
Tokai J Exp Clin Med. 1982 Nov;7(6):671-83.
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Effect of litholytic bile acids on cholesterol absorption in gallstone patients.溶石胆汁酸对胆结石患者胆固醇吸收的影响。
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Effect of oral chenodeoxycholic acid on bile acid kinetics and biliary lipid composition in women with cholelithiasis.口服鹅去氧胆酸对胆石症女性胆汁酸动力学和胆汁脂质成分的影响。
J Clin Invest. 1973 Nov;52(11):2809-21. doi: 10.1172/JCI107477.
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[Indications for medical dissolution of biliary lithiasis and value of the determination of the lithogenic index].[胆石症药物溶石的适应证及成石指数测定的价值]
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Comparative efficacy and side effects of ursodeoxycholic and chenodeoxycholic acids in dissolving gallstones. A double-blind controlled study.熊去氧胆酸和鹅去氧胆酸溶解胆结石的疗效及副作用比较:一项双盲对照研究。
Gastroenterology. 1983 Dec;85(6):1257-64.
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Chenodeoxycholic acid treatment of gallstones. A follow-up report and analysis of factors influencing response to therapy.鹅去氧胆酸治疗胆结石。随访报告及影响治疗反应因素的分析。
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Effects of biliary bile acid composition on biliary cholesterol saturation in gallstone patients treated with chenodeoxycholic acid and/or ursodeoxycholic acid.鹅去氧胆酸和/或熊去氧胆酸治疗的胆结石患者中胆汁胆汁酸组成对胆汁胆固醇饱和度的影响。
Gastroenterology. 1980 Dec;79(6):1192-8.
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Effect of chenodeoxycholic acid and phenobarbital on the rate-limiting enzymes of hepatic cholesterol and bile acid synthesis in patients with gallstones.鹅去氧胆酸和苯巴比妥对胆结石患者肝脏胆固醇及胆汁酸合成限速酶的影响。
J Lab Clin Med. 1976 Feb;87(2):281-91.
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The biochemistry of gallstone formation.胆结石形成的生物化学
Clin Gastroenterol. 1973 Jan;2(1):49-66.

引用本文的文献

1
Chenodeoxycholic acid: a review of its pharmacological properties and therapeutic use.鹅去氧胆酸:其药理特性与治疗用途综述
Drugs. 1981 Feb;21(2):90-119. doi: 10.2165/00003495-198121020-00002.