Constans J, Bakach S, Priou F, Midy D, Baste C, Beylot J, Dubroca J, Conri C
Service de Médecine Interne et Pathologie Vasculaire, Hôpital Saint-André, Bordeaux.
J Mal Vasc. 1993;18(2):144-5.
Several cases of arterial thrombosis associated with inflammatory enterocolitis affections have been reported. In all but one case reported in the literature the outcome was favorable. A 40 year old woman developed thrombosis of the radial and ulnar arteries during an acute episode of ulcerative colitis. The course of the thrombotic lesions was irreversible and all fingers of the right hand had to be amputated. The corticotherapy as a possible predisposing factor for these thromboses is discussed, but their onset during an inflammatory episode suggests a role for the inflammatory enterocolitis. A thrombocytosis (807,000 platelets/mm3) could have predisposed to their onset, and in this case the hemostatic disturbances and fibrinolysis associated with the ulcerative colitis could have played a major role.
已有多例与炎症性小肠结肠炎相关的动脉血栓形成的病例报告。文献报道的所有病例中,除了1例,其余预后均良好。一名40岁女性在溃疡性结肠炎急性发作期间出现桡动脉和尺动脉血栓形成。血栓性病变的病程不可逆,右手所有手指均需截肢。文中讨论了皮质激素治疗作为这些血栓形成的可能诱发因素,但它们在炎症发作期间出现提示炎症性小肠结肠炎起了作用。血小板增多症(血小板计数807,000/mm³)可能易导致其发生,在该病例中,与溃疡性结肠炎相关的止血障碍和纤维蛋白溶解可能起了主要作用。