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伴有脑白质疏松症和硬脑膜动静脉畸形的痴呆:临床及PET病例研究。

Dementia with leucoaraiosis and dural arteriovenous malformation: clinical and PET case study.

作者信息

Nencini P, Inzitari D, Gibbs J, Mangiafico S

机构信息

Department of Neurological and Psychiatric Sciences, University of Florence, Italy.

出版信息

J Neurol Neurosurg Psychiatry. 1993 Aug;56(8):929-31. doi: 10.1136/jnnp.56.8.929.

Abstract

A case of rapidly progressive dementia with diffuse leucoaraiosis on CT was attributable to a supratentorial dural arteriovenous malformation. Positron emission tomography (PET) showed low cerebral blood flow and high oxygen extraction ratio throughout the cerebral hemispheres indicating a state of chronic haemodynamic compromise which could predispose to the development of a vascular dementia. CT images of dilated intracerebral veins suggested that a venous drainage overload rather than a vascular steal phenomenon might be involved in the pathophysiology of the dementia of vascular origin.

摘要

一例CT显示弥漫性白质疏松的快速进展性痴呆病例归因于幕上硬脑膜动静脉畸形。正电子发射断层扫描(PET)显示整个大脑半球脑血流量低且氧摄取率高,表明存在慢性血流动力学受损状态,这可能易引发血管性痴呆。脑内静脉扩张的CT图像提示,静脉引流超负荷而非血管盗血现象可能参与了血管性痴呆的病理生理过程。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db17/1015156/39f7308a45cb/jnnpsyc00481-0092-a.jpg

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