Andrassy R J, Haff R C
Surg Gynecol Obstet. 1977 Feb;144(2):208-10.
To justify the performance of an invasive technique as an aid to determining diagnosis and therapy in any condition, one must correlate the benefits derived with the adverse effects of performing that procedure. The review of the records of the patient indicates that clinical staging remains a moderately inaccurate means of assessing the extent of the disease in patients with Hodgkin's and non-Hodgkin's lymphoma. Lymphangiogram remains an aid to the surgeon in the localization of suspicious nodes. It is of greater accuracy in the patient with Hodgkin's lymphoma as compared with those with non-Hodgkin's lymphoma. Conversely, laparotomy for staging was not of as great a value in the patients in the non-Hodgkin's group as in those in the Hodgkin's group, and the incidence of complications was higher in the non-Hodgkin's group; especially in the patients with advanced disease. Laparotomy for staging is of significant benefit in the Hodgkin's lymphoma group, and the complication rate is not prohibitive. Laparotomy for staging in the non-Hodgkin's lymphoma group, on the other hand, is of less value than it is in the Hodgkin's group and is associated with a substantially higher complication rate in the face of advanced disease. In non-Hodgkin's lymphoma, individual decisions regarding laparotomy must be used, and the routine use of laparotomy may not be warranted.
为了证明在任何情况下采用侵入性技术辅助诊断和治疗的合理性,必须将该操作带来的益处与实施该操作的不良反应联系起来。对患者病历的回顾表明,临床分期在评估霍奇金淋巴瘤和非霍奇金淋巴瘤患者的疾病范围方面仍然是一种准确性一般的方法。淋巴管造影术仍然有助于外科医生定位可疑淋巴结。与非霍奇金淋巴瘤患者相比,它在霍奇金淋巴瘤患者中具有更高的准确性。相反,分期剖腹手术在非霍奇金淋巴瘤组患者中的价值不如在霍奇金淋巴瘤组患者中那么大,并且非霍奇金淋巴瘤组的并发症发生率更高;尤其是在晚期疾病患者中。分期剖腹手术对霍奇金淋巴瘤组有显著益处,且并发症发生率并非高得令人却步。另一方面,非霍奇金淋巴瘤组的分期剖腹手术比霍奇金淋巴瘤组价值更小,并且在面对晚期疾病时并发症发生率要高得多。在非霍奇金淋巴瘤中,必须对剖腹手术进行个体化决策,常规使用剖腹手术可能并不合理。