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肝外胆管恶性肿瘤

Malignant tumors of the extrahepatic bile ducts.

作者信息

Andersson A, Bergdahl L, van der Linden W

出版信息

Surgery. 1977 Feb;81(2):198-202.

PMID:835090
Abstract

A series of 76 patients treated for carcinoma of the extrahepatic bile ducts at three Swedish hospitals during the years 1952 to 1973 was studied. The mean age of the patients was 68 years. Gallstones were found in 22 patients, whereas 11 patients had undergone cholecystectomy earlier for gallstone disease. At operation widespread metastases were found less often in patients with cancer of the papilla of Vater than in patients with cancer of other locations. This is interpreted as indicating that patients with papillary carcinoma are treated in an earlier stagage of the disease. This interpretation is supported by the finding that these patients had a longer length of survival after bypass supported by the finding that these patients had a longer length of survival after bypass supported by the finding that these patients had a longer length of survival after bypass operations (11.5 months). In spite of treatment in an early stage, survival after radical surgery was disappointingly short (4.6 months). On the other hand, patients with cancer located above the papilla of Vater survived for 6.8 months after bypass operations as compared with 23.3 months after rescetion. The possibilities of radical surgery should be considered carefully, especially in patients in whom the malignancy is located above the papillary region.

摘要

对1952年至1973年间在瑞典三家医院接受肝外胆管癌治疗的76例患者进行了研究。患者的平均年龄为68岁。22例患者发现有胆结石,而11例患者此前因胆结石疾病接受了胆囊切除术。手术时发现,与其他部位癌症患者相比, Vater乳头癌患者广泛转移的情况较少见。这被解释为表明乳头癌患者在疾病的早期阶段接受治疗。这一解释得到了以下发现的支持:这些患者在旁路手术后的生存时间更长(11.5个月)。尽管处于早期治疗,但根治性手术后的生存期短得令人失望(4.6个月)。另一方面, Vater乳头上方癌症患者在旁路手术后存活6.8个月,而切除术后存活23.3个月。应仔细考虑根治性手术的可能性,尤其是对于恶性肿瘤位于乳头区域上方的患者。

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