Lynch D A, Newell J D, Tschomper B A, Cink T M, Newman L S, Bethel R
Department of Radiology, University of Colorado Health Sciences Center, Denver 80262.
Radiology. 1993 Sep;188(3):829-33. doi: 10.1148/radiology.188.3.8351357.
A study was undertaken to define the computed tomographic (CT) appearance of the lungs in subjects with uncomplicated asthma and to compare the prevalence of bronchial dilatation at CT in asthmatic and healthy subjects. Clinical features, pulmonary physiologic findings, chest radiographs, and high-resolution CT scans of 48 asthmatic subjects were reviewed. Forty-one (85%) of the 48 asthmatic subjects were undergoing bronchodilator therapy, 28 (58%) were undergoing steroid therapy, and 21 (44%) were cigarette smokers. Twenty-seven healthy control subjects underwent limited high-resolution CT. At selected CT levels, any bronchus with an internal diameter greater than that of the accompanying pulmonary artery was considered dilated. In the asthmatic subjects, 153 (36%) of 429 bronchi evaluated met criteria for bronchial dilatation compared with 37 (26%) of 142 bronchi in the control group (P < .05). Because bronchial dilatation demonstrated at CT did not correlate with clinical data, the authors conclude a bronchus larger in diameter than the adjacent vessel is not sufficient evidence to diagnose cylindric bronchiectasis.
开展了一项研究，以明确单纯性哮喘患者肺部的计算机断层扫描（CT）表现，并比较哮喘患者与健康受试者CT检查中支气管扩张的发生率。回顾了48例哮喘患者的临床特征、肺生理检查结果、胸部X线片和高分辨率CT扫描结果。48例哮喘患者中，41例（85%）正在接受支气管扩张剂治疗，28例（58%）正在接受类固醇治疗，21例（44%）为吸烟者。27名健康对照者接受了有限的高分辨率CT检查。在选定的CT层面，任何内径大于伴行肺动脉的支气管被视为扩张。在哮喘患者中，429个评估支气管中有153个（36%）符合支气管扩张标准，而对照组142个支气管中有37个（26%）符合标准（P <.05）。由于CT显示的支气管扩张与临床数据无关，作者得出结论，直径大于相邻血管的支气管不足以作为诊断柱状支气管扩张的证据。
