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癌症患者的经皮内镜下胃造口术(PEG)

Percutaneous endoscopic gastrostomy (PEG) in cancer patients.

作者信息

Zera R T, Nava H R, Fischer J I

机构信息

Hennepin County Medical Center, Minneapolis, MN 55415.

出版信息

Surg Endosc. 1993 Jul-Aug;7(4):304-7. doi: 10.1007/BF00725945.

Abstract

Ninety-nine cancer patients underwent PEG placement attempt at Rosewell Park Cancer Institute between January 1, 1985, and December 1, 1987. Ninety-eight of these were successful and were retrospectively reviewed to determine if cancer patients constitute a high-risk group for PEG placement. Procedure-related mortality was 2% and morbidity was 19%. Morbidity of 17% was noted at less than 30 days and 2% had late complications. Six complications were considered serious with peritonitis in 3 and tube loss in 3 patients; an additional 4 patients had a failure of adequate GI tract decompression which was the indication for their PEG placement. Ascites was a major factor in morbidity with 4 of 5 patients with ascites having complications including the 2 deaths. Overall major morbidity was not increased in cancer patients without ascites including a group of patients with carcinomatosis (18 patients) and 22 patients requiring preoperative dilatation and/or tumor ablative procedures. We conclude that morbidity in cancer patients is not increased if one excludes those with ascites from the procedure.

摘要

1985年1月1日至1987年12月1日期间,99例癌症患者在罗斯韦尔帕克癌症研究所尝试进行经皮内镜下胃造口术(PEG)置管。其中98例成功,并进行回顾性分析,以确定癌症患者是否属于PEG置管的高危人群。与操作相关的死亡率为2%,发病率为19%。17%的患者在30天内出现并发症,2%的患者出现晚期并发症。6例并发症被认为较为严重,3例发生腹膜炎,3例出现造瘘管脱落;另有4例患者胃肠道减压不足,这也是他们进行PEG置管的指征。腹水是导致发病的主要因素,5例腹水患者中有4例出现并发症,包括2例死亡。在没有腹水的癌症患者中,总体严重并发症并未增加,这组患者包括一组癌性腹膜炎患者(18例)以及22例需要术前扩张和/或肿瘤消融手术的患者。我们得出结论,如果在该操作中排除有腹水的患者,癌症患者的并发症发生率不会增加。

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