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癌症患者经皮内镜下胃造口管置入术的并发症:一项回顾性研究。

Complications of percutaneous endoscopic gastrostomy tube insertion in cancer patients: a retrospective study.

作者信息

Mansoor Hala, Masood Muhammad Adnan, Yusuf Muhammed Aasim

机构信息

Shaukat Khanum Memorial Cancer Hospital & Research Centre, Lahore, Pakistan,

出版信息

J Gastrointest Cancer. 2014 Dec;45(4):452-9. doi: 10.1007/s12029-014-9630-y.

DOI:10.1007/s12029-014-9630-y
PMID:24965355
Abstract

AIM

Dysphagia, with associated malnutrition is a common feature in up to 64 % of patients with cancers of the head and neck region, the oesophagus and the gastro-oesophageal junction (Donaldson and Lenon Cancer 43(Suppl 5):2036-52, 1979). These patients usually require alternate routes of feeding during treatment. However, these methods of feeding are not without associated complications. This study was carried out to assess the complications associated with percutaneous endoscopic gastrostomy tube insertion, the commonest means of providing nutrition in this patient group.

METHODS

Two hundred and sixty patients with successful percutaneous endoscopic gastrostomy (PEG) tube insertion were retrospectively reviewed to assess the complications of the procedure.

RESULTS

The overall complication rate was 25 % (65 patients). Fifty-five patients (21 %) patients had minor complications. Ten patients (3.8 %) suffered a major complication, including peritonitis and major peri-PEG infection each in three patients (1.2 %), while oesophageal perforation, collection around the PEG insertion site requiring operative drainage, bleeding from the PEG insertion site and tumour seeding at the gastrostomy site were each seen in one (0.4 %) patient.

CONCLUSION

Percutaneous endoscopic gastrostomy tube insertion is a useful means of providing enteral nutrition to patients with swallowing problems. Patients with head and neck cancer who are likely to develop dysphagia should be assessed promptly for PEG tube insertion before the start of radiation. Early recognition and prompt treatment of serious complications can avoid potential fatality associated with PEG tubes.

摘要

目的

吞咽困难伴营养不良是高达64%的头颈部癌症、食管癌和胃食管交界处癌症患者的常见特征(唐纳森和勒农,《癌症》43(增刊5):2036 - 2052,1979年)。这些患者在治疗期间通常需要通过其他途径进食。然而,这些进食方法并非没有相关并发症。本研究旨在评估经皮内镜下胃造口管置入术(该患者群体中最常用的营养供给方式)相关的并发症。

方法

对260例成功进行经皮内镜下胃造口术(PEG)置管的患者进行回顾性研究,以评估该手术的并发症。

结果

总体并发症发生率为25%(65例患者)。55例患者(21%)出现轻微并发症。10例患者(3.8%)发生严重并发症,包括3例(1.2%)患者发生腹膜炎和PEG周围严重感染,而食管穿孔、PEG插入部位周围积液需要手术引流、PEG插入部位出血以及胃造口部位肿瘤种植各有1例(0.4%)患者出现。

结论

经皮内镜下胃造口管置入术是为吞咽困难患者提供肠内营养的有效方法。可能发生吞咽困难的头颈部癌症患者应在放疗开始前及时评估是否适合进行PEG置管。对严重并发症的早期识别和及时治疗可避免与PEG管相关的潜在死亡。

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J Radiat Res. 2014 May;55(3):559-67. doi: 10.1093/jrr/rrt144. Epub 2014 Jan 22.
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Repeat PEG placement is safe for head and neck cancer patients.重复放置经皮内镜下胃造口术(PEG)对头颈癌患者是安全的。
Am J Otolaryngol. 2014 Mar-Apr;35(2):89-92. doi: 10.1016/j.amjoto.2013.12.001. Epub 2013 Dec 12.
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Usefulness of percutaneous endoscopic gastrostomy for supportive therapy of advanced aerodigestive cancer.
经皮内镜下胃造口术在晚期上消化道癌症支持治疗中的应用价值
World J Gastrointest Pathophysiol. 2013 Nov 15;4(4):119-25. doi: 10.4291/wjgp.v4.i4.119.
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Prospective evaluation of malignant cell seeding after percutaneous endoscopic gastrostomy in patients with oropharyngeal/esophageal cancers.经皮内镜胃造瘘术后口咽/食管恶性肿瘤患者癌细胞种植的前瞻性评估。
Endoscopy. 2013 Jul;45(7):526-31. doi: 10.1055/s-0033-1344023. Epub 2013 Jun 18.
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Enteral feeding methods for nutritional management in patients with head and neck cancers being treated with radiotherapy and/or chemotherapy.对头颈部癌症患者进行放疗和/或化疗时,用于营养管理的肠内喂养方法。
Cochrane Database Syst Rev. 2013 Jan 31;2013(1):CD007904. doi: 10.1002/14651858.CD007904.pub3.
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Comparison of modified introducer method with pull method for percutaneous endoscopic gastrostomy: prospective randomized study.改良穿刺器法与拉提法行经皮内镜胃造口术的比较:前瞻性随机研究。
Dig Endosc. 2012 Nov;24(6):426-31. doi: 10.1111/j.1443-1661.2012.01317.x. Epub 2012 Apr 26.
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