Creasey G H
Applied Neural Control Laboratory, Case Western Reserve University, Cleveland, Ohio.
Urol Clin North Am. 1993 Aug;20(3):505-15.
In patients with suprasacral spinal cord injury, electrical stimulation of the sacral anterior nerve roots can produce micturition with low residual volumes of urine and reduced urinary tract infection. Voiding pressures can be maintained at acceptable levels by selective peripheral neurotomy and myotomy or, more commonly, by an intermittent pattern of stimulation. Occasionally, external sphincterotomy is required. The procedure is usually combined with division of the sacral posterior roots, which increases bladder capacity and continence; this also increases bladder compliance, which may be protective for the upper urinary tracts. A reduction in constipation usually is observed, and some patients are able to defecate with the aid of electrical stimulation. Penile erection is produced in a substantial proportion of male patients. The procedure has now been applied in about 700 patients with spinal cord injury, some of whom have been followed for nearly 15 years. The nerves do not appear to be damaged by long-term stimulation, and technical faults with the equipment are now uncommon.
在骶上脊髓损伤患者中,电刺激骶前神经根可产生残余尿量少且尿路感染减少的排尿。通过选择性外周神经切断术和肌切开术,或更常见的是通过间歇性刺激模式,可将排尿压力维持在可接受水平。偶尔需要进行外括约肌切开术。该手术通常与骶后根切断术相结合,这会增加膀胱容量和控尿能力;这也会增加膀胱顺应性,这可能对上尿路起到保护作用。通常会观察到便秘有所减轻,一些患者能够借助电刺激排便。相当一部分男性患者会出现阴茎勃起。该手术现已应用于约700例脊髓损伤患者,其中一些患者已被随访近15年。长期刺激似乎不会损伤神经,设备的技术故障现在也不常见。