McLean R G, Kirk L J, Shriner R B, Townsend M
Division of Vector-Borne Infectious Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, Colorado.
Am J Trop Med Hyg. 1993 Jul;49(1):46-52. doi: 10.4269/ajtmh.1993.49.46.
An investigation of the extent of St. Louis encephalitis (SLE) virus activity in the avian population in Pine Bluff, Arkansas was conducted from August 30, 1991 through September 5, 1991, following an SLE epidemic that resulted in 25 human cases. A total of 363 birds of 33 species were captured with ground-level mist nets at four sites along the northern edge of the city. No viruses were isolated from the serum of these birds, but 91 birds (25%) of 11 species had detectable neutralizing antibody against the TBH-28 strain of SLE virus in the constant-virus, serum-dilution, plaque-reduction neutralization test in Vero cell culture. No antibody to eastern equine encephalitis virus was detected. The prevalence of antibody to SLE virus varied among the sites from 11% to 44%, but the prevalence at each site was influenced by the avian species composition. The two most abundant species captured in the city, the American robin (43%) and house sparrow (42%), also had the highest prevalence of antibody. Nine other bird species were serologically positive but at significantly lower rates than for the abundant species. The antibody prevalence was higher in immature birds (27%) than in adult birds (15%), but the antibody titers were higher in adult birds than in immature ones. The overall SLE antibody prevalence and the prevalence for house sparrows were significantly higher than the average prevalence for avian hosts studied during previous SLE epidemics. Therefore, house sparrows would be a good choice for a local sentinel species.
1991年8月30日至9月5日，在阿肯色州派恩布拉夫发生圣路易斯脑炎（SLE）疫情并导致25例人类病例后，对该市鸟类群体中SLE病毒的活动范围进行了调查。在城市北部边缘的四个地点，用地面薄雾网捕获了33个物种的363只鸟。从这些鸟类的血清中未分离出病毒，但在Vero细胞培养的恒定病毒、血清稀释、蚀斑减少中和试验中，11个物种的91只鸟（25%）对SLE病毒的TBH - 28株具有可检测到的中和抗体。未检测到针对东部马脑炎病毒的抗体。SLE病毒抗体的流行率在各地点之间从11%到44%不等，但每个地点的流行率受鸟类物种组成的影响。在该市捕获的数量最多的两个物种，美洲知更鸟（43%）和家麻雀（42%），也具有最高的抗体流行率。其他9种鸟类血清学呈阳性，但比率明显低于数量较多的物种。幼鸟的抗体流行率（27%）高于成年鸟（15%），但成年鸟的抗体滴度高于幼鸟。总体SLE抗体流行率和家麻雀的流行率显著高于先前SLE疫情期间研究鸟类宿主的平均流行率。因此，家麻雀将是当地哨兵物种的一个不错选择。
