Kawazoe T, Hongo S, Takeda M, Sato T
2nd Department of Biochemistry, School of Medicine, Showa University, Tokyo, Japan.
Anticancer Res. 1993 Jul-Aug;13(4):1223-9.
A water extract of wood chips of coniferous slash pine induced appreciable splenocyte-mitogenesis in healthy adult, aged, and also tumour-bearing mice. Mitogenesis was induced mainly in B-cell subset of splenocytes. The induction was not mediated by IL-2 or IFN gamma released from the activated helper T-cell. It may be worth noting that this extract could be included in a new type of immunomodulator for promotion of the host defense mechanism.
