Gutrecht J A, Zamani A A, Slagado E D
Department of Neurology, Lahey Clinic, Burlington, Mass 01805.
Arch Neurol. 1993 Aug;50(8):849-51. doi: 10.1001/archneur.1993.00540080056014.
To test the presumption that Lhermitte's sign in multiple sclerosis is the result of a lesion in the cervical spinal cord.
The radiologic files of 887 patients with multiple sclerosis were reviewed. A detailed questionnaire regarding Lhermitte's sign was sent to 75 patients who had undergone magnetic resonance imaging of the brain and cervical spinal cord. Of the 64 patients who responded, 55 patients who had complete magnetic resonance imaging files were studied. The cases of two illustrative patients are presented.
A strong association between Lhermitte's sign and abnormalities of the cervical spinal cord seen on magnetic resonance imaging was noted. Most of the abnormalities were in the posterior part of the cervical spinal cord.
The findings confirm the presumption that a lesion in the posterior columns of the cervical spinal cord is the cause of Lhermitte's sign in multiple sclerosis.
验证多发性硬化症中莱尔米特征象是由颈脊髓病变所致的假设。
回顾了887例多发性硬化症患者的放射学档案。向75例接受过脑部和颈脊髓磁共振成像检查的患者发送了一份关于莱尔米特征象的详细问卷。在64例回复的患者中，对55例有完整磁共振成像档案的患者进行了研究。并展示了两名典型患者的病例。
注意到莱尔米特征象与磁共振成像显示的颈脊髓异常之间存在密切关联。大多数异常位于颈脊髓后部。
这些发现证实了颈脊髓后柱病变是多发性硬化症中莱尔米特征象病因的假设。
