[不同制备工艺对双黄连注射液中黄芩苷含量的影响]

[Effect of different preparation crafts on the content of baicalin in shuanghuanglian (SHL) injection].

作者信息

Miao L, Chen G W, Song Y X, Yan R C, Jia B L, Pu Y C, Huang Y X

机构信息

First Affiliated Hospital of Harbin Medical University.

出版信息

Zhongguo Zhong Yao Za Zhi. 1993 Mar;18(3):156-7, 191.

PMID:8352901

Abstract

The content of baicalin is stable when baicalin is added quantitatively in preparation. The time of extraction of the effective components of SHL with alcohol and the concentration of alcohol have little effect on the content of baicalin. The components can be extracted once, and the content of alcohol is preferably 85%. The pH level has greater influence on the content of baicalin, and should be controlled between 7.0 to 8.0. 0.2% activated carbon is suitable in preparation.

摘要

在制剂中定量加入黄芩苷时，黄芩苷含量稳定。用乙醇提取双黄连有效成分的时间及乙醇浓度对黄芩苷含量影响较小。成分可一次性提取，乙醇含量以85%为宜。pH值对黄芩苷含量影响较大，应控制在7.0至8.0之间。制剂中适宜加入0.2%的活性炭。