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[短暂性脑缺血发作中认知功能衰退的评估]

[The evaluation of cognitive deterioration in transient ischemic attacks].

作者信息

López Gastón J I, Martín J, Bertol V, Errea J M, Pina M A

机构信息

Servicio de Neurología, Hospital Miguel Servet, Zaragoza.

出版信息

Neurologia. 1993 Jun-Jul;8(6):171-6.

PMID:8352972
Abstract

We compared the degree of dementia in a group of 41 patients who, four years previously, had presented a first TIA with that of 31 healthy controls of similar age. For pathogenic diagnosis the Hachinski and Gustafson-Nilsson scales were applied, while mental state was evaluated by the Folstein, Blessed, GDS and CDR tests. We performed in all cases cerebral CT and several MR. The findings associated with dementia were the presence of multi-infarctions, leucoaraiosis or lacunes in the cerebral CT and the presentation of new ischemic episodes, sphincterian or gait disturbances and focal deficits. There were no differences with the control group in the cases only presenting one TIA. Polyglobulia was the only factor significantly associated with vascular dementia in these patients.

摘要

我们比较了一组41例患者的痴呆程度,这些患者在四年前首次出现短暂性脑缺血发作(TIA),并与31名年龄相仿的健康对照者进行了比较。为了进行病因诊断,应用了哈金斯基(Hachinski)量表和古斯塔夫森-尼尔森(Gustafson-Nilsson)量表,同时通过福尔斯坦(Folstein)、布莱斯德(Blessed)、老年抑郁量表(GDS)和临床痴呆评定量表(CDR)测试来评估精神状态。我们对所有病例都进行了脑部CT和多项磁共振成像(MR)检查。与痴呆相关的发现包括脑部CT出现多发梗死、脑白质疏松或腔隙,以及出现新的缺血性发作、括约肌或步态障碍和局灶性缺损。仅出现一次TIA的病例与对照组没有差异。红细胞增多症是这些患者中与血管性痴呆显著相关的唯一因素。

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