Morgan J M, Lynn S, Gillespie J I, Greenwell J R
Department of Physiological Sciences, Medical School, University of Newcastle upon Tyne, UK.
Biochim Biophys Acta. 1993 Aug 20;1158(1):98-102. doi: 10.1016/0304-4165(93)90102-e.
Cells maintained in serum free medium for 24 hours were found to have a higher incidence of both spontaneous increases in intracellular calcium ([Ca2+]i) (Ca2+ spikes) and small random changes in [Ca2+]i (Ca2+ 'noise'). The spontaneous transient increases in [Ca2+]i and the Ca2+ 'noise' disappear in solutions containing nominally zero Ca2+.
在无血清培养基中培养24小时的细胞被发现，细胞内钙（[Ca2+]i）的自发增加（Ca2+ 尖峰）和[Ca2+]i的小随机变化（Ca2+ “噪声”）的发生率都更高。在名义上钙浓度为零的溶液中，[Ca2+]i的自发瞬时增加和Ca2+ “噪声”消失。
