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[从大鼠心肌中分离出的中分子茚三酮阳性物质对乙醇给药后大鼠血清芳基酰胺酶活性的影响]

[The effect of middle-molecular ninhydrin-positive substances isolated from the rat myocardium on rat serum arylamidase activity after administration of ethanol].

作者信息

Chavková Z, Surzin J, Adam J

机构信息

Katedra lekárskej chémie a biochémie LF UPJS v Kosiciach, Slovakia.

出版信息

Bratisl Lek Listy. 1993 Jan;94(1):24-9.

PMID:8353735
Abstract

Protein-free extract from the myocardium of control rats and the majority of its fractions were found to stimulate arylamidase activity. Ethanol administration to rats for 1, 3 or 7 weeks increased the amount of fractions which displayed an inhibitory effect. The observed changes were probably due to enhanced protein degradation and/or to decreased amino acid incorporation into proteins following ethanol administration. (Tab. 4, Fig. 2, Ref. 19.).

摘要

对照大鼠心肌的无蛋白提取物及其大部分组分被发现可刺激芳基酰胺酶活性。给大鼠喂食乙醇1、3或7周会增加具有抑制作用的组分的量。观察到的变化可能是由于乙醇给药后蛋白质降解增强和/或氨基酸掺入蛋白质减少所致。(表4,图2,参考文献19)

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