Kohno I, Ishii H, Nakamura T, Tamura K
2nd Department of Internal Medicine, Yamanashi Medical College, Japan.
Chronobiologia. 1993 Jan-Jun;20(1-2):53-61.
In 17 healthy Japanese students (14 males and 3 females) an ambulatory activity level monitoring instrument (Actigraph) was attached to the wrist for 48-hour measurement of wrist movement (with 0.01G or higher acceleration). At the same time, an ambulatory blood pressure monitoring apparatus was attached to these subjects to monitor blood pressure (BP) and heart rate (HR) every 30 minutes. Sleeping hours were calculated from the activity levels. The sleeping hours obtained by the Actigraph correlated with those judged from the diary. The correlation was better for the go-to-sleep time than for the awakening time. Activity level, HR and BP showed a similar circadian variation. Activity level differed significantly between the active daytime (4500 counts/hour) and during sleep at night (720 counts/hour). The acrophase of activity level, obtained by the cosinor method, was 235 degrees which did not significantly differ from that of BP and HR. Hourly activity levels correlated with HR and BP at corresponding hours. These results suggest that BP is affected by activity levels even if this rhythm continues to recur in bedrest.
在17名健康的日本学生（14名男性和3名女性）中，将一种动态活动水平监测仪器（活动记录仪）附着在手腕上，进行48小时的手腕运动测量（加速度为0.01G或更高）。同时，给这些受试者佩戴动态血压监测设备，每30分钟监测一次血压（BP）和心率（HR）。根据活动水平计算睡眠时间。活动记录仪测得的睡眠时间与日记判断的睡眠时间相关。入睡时间的相关性比醒来时间更好。活动水平、心率和血压呈现相似的昼夜变化。白天活跃时（4500次计数/小时）和夜间睡眠时（720次计数/小时）的活动水平有显著差异。通过余弦法获得的活动水平的峰值相位为235度，与血压和心率的峰值相位无显著差异。每小时的活动水平与相应时间的心率和血压相关。这些结果表明，即使这种节律在卧床休息时持续出现，血压也会受到活动水平的影响。
