Wioland M, Bonnerot V
Service de Médecine Nucléaire, Hôpital Saint-Antoine, Paris, France.
J Nucl Med. 1993 Sep;34(9):1410-5.
Bone single-photon emission computed tomography (SPECT), capable of creating maps of the distribution of osteoblastic activity in every spatial plane of a physis, should provide images of diagnostic value in the case of patients suffering from growth arrests (epiphysiodeses). Seventy-five bone SPECT scans were obtained in 64 children suspected to have developed physeal arrests. The transaxial slices of the physis, in the case of partial epiphysiodeses: (a) indicated the percentage of the remaining normal physis, (b) located the bony bridge within the physis and (c) showed the slowdown of the growth of the remaining normal physis induced by the bony bridge in some children. Misdiagnosis occurred in six patients. For total epiphysiodeses, the radionuclide diagnosis was confirmed in 20 of 21 patients. Radionuclide, x-ray and MRI examinations in the study of growth disturbances were found to be complementary.
骨单光子发射计算机断层扫描(SPECT)能够生成骨骺每个空间平面的成骨细胞活动分布图,对于患有生长停滞(骨骺固定)的患者,它应该能提供具有诊断价值的图像。对64名疑似发生骨骺停滞的儿童进行了75次骨SPECT扫描。对于部分骨骺固定的情况,骨骺的横断面切片:(a)显示剩余正常骨骺的百分比,(b)确定骨骺内骨桥的位置,(c)显示在一些儿童中,骨桥导致剩余正常骨骺生长减缓。6名患者出现误诊。对于完全骨骺固定,21例患者中有20例经放射性核素诊断得到证实。研究发现,放射性核素、X线和MRI检查在生长障碍研究中具有互补性。