Albanese C T, Towbin R B, Ulman I, Lewis J, Smith S D
Department of Pediatric Surgery, Children's Hospital of Pittsburgh, PA 15213-2583.
J Pediatr. 1993 Sep;123(3):371-5. doi: 10.1016/s0022-3476(05)81734-2.
To determine the optimal method of providing enteral feeding to neurologically impaired children with gastroesophageal reflux, Nissen fundoplication with simultaneous gastrostomy tube placement (NGT) was compared with anterograde percutaneous gastrojejunostomy (APGJ), a nonsurgical procedure performed under fluoroscopic guidance. The records of 112 neurologically impaired children with gastroesophageal reflux were retrospectively reviewed; 68 had undergone NGT and 44 APGJ. Follow-up data were available for 45 NGT patients (mean age, 6.4 years) and 34 APGJ patients (mean age, 7.9 years). Mean follow-up was 1.8 years in the NGT group and 2.5 years in the APGJ group. Complications resulting from either procedure were classified either as major, which included treatment failures or morbidity resulting in prolonged hospitalization, or as minor, those requiring outpatient treatment only or not directly caused by the procedure. The NGT group had a significantly higher incidence of major complications in comparison with the APGJ group (33.3% vs 11.8%, p < 0.05). Ten patients (22.2%) in the NGT group required reoperation for complications; six required a second NGT for wrap hernia, failure, and continued gastroesophageal reflux. Two patients (5.9%) in the APGJ group required surgery for complications; one of these eventually required an NGT, and the other had an intussusception that necessitated a small-bowel resection. Minor complications were more common in the APGJ group than in the NGT group (44.1% vs 6.6%); the majority of complications were related to the jejunostomy tube. Premature replacement or reinsertion of the jejunostomy tube was necessary in 14 APGJ patients (32%). The mortality rate was 8.8% in the NGT group and 5.9% in the APGJ group (p = not significant). No death occurred within 30 days of either procedure. We conclude that APGJ is a safe alternative method for feeding the neurologically impaired child with gastroesophageal reflux.
为确定为患有胃食管反流的神经功能受损儿童提供肠内喂养的最佳方法,对同时进行胃造口管置入术(NGT)的nissen胃底折叠术与在透视引导下进行的非手术顺行性经皮胃空肠造口术(APGJ)进行了比较。回顾性分析了112例患有胃食管反流的神经功能受损儿童的记录;68例行NGT,44例行APGJ。45例NGT患者(平均年龄6.4岁)和34例APGJ患者(平均年龄7.9岁)有随访数据。NGT组平均随访1.8年,APGJ组平均随访2.5年。两种手术引起的并发症分为严重并发症(包括治疗失败或导致住院时间延长的发病率)和轻微并发症(仅需门诊治疗或不是直接由手术引起的并发症)。与APGJ组相比,NGT组严重并发症的发生率显著更高(33.3%对11.8%,p<0.05)。NGT组有10例患者(22.2%)因并发症需要再次手术;6例因包裹性疝、失败和持续胃食管反流需要再次行NGT。APGJ组有2例患者(5.9%)因并发症需要手术;其中1例最终需要行NGT,另1例发生肠套叠,需要行小肠切除术。APGJ组轻微并发症比NGT组更常见(44.1%对6.6%);大多数并发症与空肠造口管有关。14例APGJ患者(32%)需要过早更换或重新插入空肠造口管。NGT组死亡率为8.8%,APGJ组死亡率为5.9%(p无统计学意义)。两种手术30天内均未发生死亡。我们得出结论,APGJ是喂养患有胃食管反流的神经功能受损儿童的一种安全替代方法。