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[单肾患者肾血管性高血压的外科治疗]

[The surgical treatment of renovascular hypertension in subjects with a single kidney].

作者信息

Ghilardi G, Longhi F, Bortolani E, Giuffrida G F, Vandone P L, Negri L

机构信息

Istituto di Chirurgia Generale e Cardiovascolare, Università degli Studi di Milano.

出版信息

Minerva Chir. 1993 May 15;48(9):465-70.

PMID:8355875
Abstract

Renovascular hypertension in subjects with a solitary kidney, though an infrequent condition, requires surgical direct revascularization procedures either to reduce the hypertensive state and, more important, to preserve renal function. This paper reports a series of six surgically treated cases between 1982 and 1990, with at least two years follow-up. Preoperative renal function, as evaluated by BUN and blood creatinine, was reduced in 5 cases, the remaining one being normal. All subjects were hypertensive at admission: in four cases drug therapy was ineffective for restoring normal pressure values. All subjects had previously undergone surgical nephrectomy: in 3 cases for shrunk kidney, in 2 for failure of a previous attempt of renal revascularization, and one for renal tuberculosis. 3 subjects were concomitantly affected with abdominal aortic aneurysm, and one had previously undergone aortobifemoral bypass. Treatment of the concomitant aortic lesion and renal artery revascularization were carried out at the same operation. Operations performed were TEA of residual renal artery in 3 cases, prosthetic reconstruction in 2 and intraoperative transluminal angioplasty by Gruentzig balloon catheter in one. Over a two-year follow-up renal function remained good in 4 cases, while one subject required a second surgical revascularization due to late acute thrombosis of a previous aortorenal saphenous vein graft. Acute early postoperative renal failure occurred in one case and permanent haemodialysis was instituted. No deaths were recorded in this series.

摘要

孤立肾患者的肾血管性高血压虽然并不常见,但需要进行手术直接血管重建术,以降低高血压状态,更重要的是保护肾功能。本文报告了1982年至1990年间接受手术治疗的6例患者,随访至少两年。术前通过血尿素氮和血肌酐评估,5例患者肾功能降低,其余1例正常。所有患者入院时均患有高血压:4例患者药物治疗无法恢复正常血压值。所有患者此前均接受过手术肾切除术:3例因肾萎缩,2例因先前肾血管重建术失败,1例因肾结核。3例患者同时患有腹主动脉瘤,1例患者先前接受过主动脉双股动脉搭桥术。在同一手术中进行了伴随主动脉病变的治疗和肾动脉血管重建术。实施的手术包括3例残余肾动脉的血栓内膜剥脱术(TEA),2例人工血管重建术,1例通过Gruentzig球囊导管进行术中腔内血管成形术。经过两年的随访,4例患者肾功能良好,而1例患者因先前的主动脉-肾隐静脉移植后期急性血栓形成需要再次进行手术血管重建术。1例患者术后早期发生急性肾衰竭并开始进行永久性血液透析。该系列中无死亡病例记录。

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