Kweider M, Lowe G D, Murray G D, Kinane D F, McGowan D A
Department of Oral Surgery, Dental Hospital & School, Glasgow.
Scott Med J. 1993 Jun;38(3):73-4. doi: 10.1177/003693309303800304.
Plasma fibrinogen and white blood cell count were compared in fifty patients aged 25-50 years with periodontal disease and in fifty age-matched controls with relatively healthy periodontal tissues. Patients had significantly higher levels of fibrinogen and white cell count, and dental indices correlated significantly with these two cardiovascular risk factors on multivariate analyses. We suggest that inflammatory dental disease may be a determinant of fibrinogen level and white cell count in the general population, and that fibrinogen and white cell count may be two mediators of the link between dental disease and myocardial infarction.
对50名年龄在25至50岁之间患有牙周疾病的患者以及50名年龄匹配、牙周组织相对健康的对照者的血浆纤维蛋白原和白细胞计数进行了比较。患者的纤维蛋白原水平和白细胞计数显著更高，并且在多变量分析中，牙齿指数与这两个心血管危险因素显著相关。我们认为，炎症性牙齿疾病可能是普通人群中纤维蛋白原水平和白细胞计数的一个决定因素，并且纤维蛋白原和白细胞计数可能是牙齿疾病与心肌梗死之间联系的两个介导因素。
