Funahashi H, Satoh Y, Imai T, Ohno M, Narita T, Katoh M, Tanaka Y, Tobinaga J, Andoh H, Miyazaki K
Department of Surgery II, Nagoya University School of Medicine, Japan.
Surgery. 1993 Jul;114(1):92-6.
For papillary thyroid carcinoma, we have used our standard operative method consisting of total thyroidectomy, bilateral lymph node dissection, and parathyroid autotransplantation. Our special parathyroid transplantation method involves transplantation of the minced glands into the pectoralis major muscle. We investigated whether this method is useful for preserving parathyroid function.
In 17 patients who underwent our standard operation for papillary thyroid carcinoma, the intact parathyroid hormone (PTH) and serum calcium levels were determined for 4 weeks after the operation.
In all cases the intact PTH levels fell below detectable limits immediately after operation and then recovered to the preoperative level about 2 weeks after the operation. The same recovery patterns were observed in two groups undergoing transplantation of two glands and three or four glands.
These recovery patterns of intact PTH levels seem to indicate that the glands were grafted successfully and recovered their function. Our method is thought to be useful for preserving parathyroid function after surgery.
对于甲状腺乳头状癌,我们采用了包括甲状腺全切除术、双侧淋巴结清扫术和甲状旁腺自体移植术在内的标准手术方法。我们特殊的甲状旁腺移植方法是将切碎的腺体移植到胸大肌中。我们研究了这种方法是否有助于保留甲状旁腺功能。
对17例行甲状腺乳头状癌标准手术的患者,术后4周测定其完整甲状旁腺激素(PTH)和血清钙水平。
所有病例术后即刻完整PTH水平均降至检测限以下,术后约2周恢复至术前水平。在接受两个腺体移植和三个或四个腺体移植的两组中观察到相同的恢复模式。
完整PTH水平的这些恢复模式似乎表明腺体移植成功并恢复了功能。我们的方法被认为有助于术后保留甲状旁腺功能。